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The Truth About GLP-1 Medications and Muscle Loss – What You Need to Know
On Ozempic, Mounjaro, or Wegovy? Discover why strength training is essential to preserve muscle mass and improve long-term results.
By
August 11, 2025

GLP-1 medications like Ozempic, Mounjaro, and Wegovy have become popular tools in weight loss-but they come with a hidden risk: losing muscle along with fat.
And that’s a problem.
Here’s why strength training is non-negotiable if you’re taking these medications:
1. You’re Losing More Than Just Fat
Research shows that up to 30–40% of the weight lost on GLP-1s can come from muscle-unless you actively work to prevent it.
2. Muscle = Your Metabolic Engine
More muscle means better metabolism, blood sugar regulation, and strength. Lose too much, and your energy tanks and your long-term results suffer.
3. Strength Training Helps You Keep It Off
Muscle helps prevent rebound weight gain. It gives your body structure, stability, and performance-especially when your appetite is suppressed.
4. Protein + Progressive Overload Is Key
GLP-1s reduce hunger, so eating enough protein can be tough. Combined with a structured strength program, you’ll retain lean tissue and feel stronger—even while dropping pounds.
🔥 We train plenty of members who are navigating GLP-1s—and we help them do it safely, effectively, and with strength in mind.
No shame. No fads. Just facts.
👉 Start with a free class or join our 14-day reset designed to build lean muscle and confidence.